I wonder how anyone uses GMail or GReader without keystrokes...
Seriously folks, J and K.
Start there.
It'll change your life.
I'm constantly amazed when I talk to "long time" GMail (or more rarely but more encouraging) Google Reader users who don't use the J or K or "tab + send" or the plethora of keyboard shortcuts that make these platforms SO much more valuable and intuitive.
I'm beginning to suspect that GMail is still behind Hotmail and Yahoo Mail in terms of adoption because folks haven't discovered J/K, Shift+1, Shift+3, Y, E, etc...